I remember the crushing fatigue and hope that I never have to feel that way again. I was on Plaquenil for over a year with my Limited Systemic Sclerosis and didn't notice any effect, scleroderma still progressing. :( Next week I am going to consult with my scleroderma doc what next. It's generally prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. I remained on that dosage for the first five years. You have to have you eyes checked on a very regular basis as it can cause visual changes and difficulty. Chloroquine and hydroxychloroquine rheumatoid arthritis Malaria tablets chloroquine Cornea verticillata plaquenil A loading dose of 1,200 mg daily, given for 6 weeks may decrease the time to clinical response. However, experts debate that this higher dosage may increase the risk of toxicity. Hydroxychloroquine can be taken in a single or divided dose to control gastrointestinal side effects. Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. Generally, hydroxychloroquine is given in 200 mg or 400 mg doses, once per day. Higher doses can sometimes be used, but only in adults and not for all cases. Some people tolerate this medication much better than other people, so it is important that individuals who are considering taking hydroxychloroquine talk with their doctor about the lowest necessary dose to reduce or eliminate their symptoms. But it had an almost immediate effect for me with respect to fatigue, which I attribute to it's effect on vitamin D regulation (or dysregulation in my case). There have been times when I've stopped taking it over the years and have noticed no change in my fatigue or pain levels. The swelling/tendonitis in my fingers & toes stopped progressing after about 3 months, but 9 months later, they are still somewhat stiff and swollen, so it's difficult to know what would have happened without it. After that I was dropped to 200 mg two times a day. It's been a long time since I began taking it, but I don't remember any increase in energy. 200 mg of plaquenil how long to work Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., RA and Hydroxychloroquine How Effective is it for Rheumatoid. Plaquenil toxicity guildelineIs plaquenil bad for your eyesChloroquine online pharmacy Mark a calendar to help you remember. This drug is usually started 2 weeks before entering the area with malaria. Take it once weekly while in the area, and continue taking it for 4 to 8 weeks after leaving the area or as directed by your doctor. To treat malaria, follow your doctor's instructions. Plaquenil Oral Uses, Side Effects, Interactions.. RA and Hydroxychloroquine How Effective is it for.. How is plaquenil hydroxychloroquine used to treat lupus?. I started generic plaquenil mid-may. I feel good but wonder if I will be able to cut the dose from 200 mg. twice a day and how long I have to be on it. Or if i can just take it when neccesary. My doctor is in the process of being absorbed into another medical group and is hard to reach for now. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Re Plaquenil - Can It Work Quickly? I tried to get on Plaquenil years ago, and couldn't tolerate it, but now I'm thinking there might be a lessor dose I should try. I'm new to the area, so don't have a rheumy yet.