It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil toxicity eye Plaquenil contraindications Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Although they are uncommon, Plaquenil has side effects that may affect your eyes. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Nov 28, 2010 Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation when an infection is found, and these basically malfunction with inflammatory disorders. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. What conditions does plaquenil treat Conditions Plaquenil-related Eye Problems Eugene Eye Care, Hydroxychloroquine Side Effects, Dosage, Uses, and More Ddo you have to stop plaquenil slowly Commonly known by its old brand-name Plaquenil were first used to treat malaria, but the malaria-causing organism soon became resistant to them. However, during the treatment of patients with malaria who also had lupus, it was noted that their skin rashes improved. Plaquenil Use in Autoimmune Diseases. Inflammatory Osteoarthritis And Plaquenil. The Risk of Retinal Toxicity with Plaquenil. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment. I used Plaquenil years ago for extreme muscle and joint issues and it seemed to work fine. All my issues were resolved over a years time on low doses. I believe my problems started with side effects of a statin, which I stopped taking during my Plaquenil treatment but resumed after symptoms were resolved.