Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Recommended eye for sjogrens plaquenil Hydroxychloroquine itchy scalp Incidence of plaquenil retinopathy Using chloroquine in display reef tank Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so. Patients with pre-existing retinopathy of the eye — this is a relative contraindication in that it makes patient monitoring more difficult. Tell me more about hydroxychloroquine. Hydroxychloroquine has a lower risk of ocular toxicity, both corneal and retinal, compared with chloroquine. AAO MONITORING GUIDELINES With an estimated 150,000 patients taking hydroxychloroquine at any one time in the United States, 1 the resource burden on the US health care system for routine retinal toxicity monitoring is potentially significant. In the package insert for the drug, the manufacturer recommends ophthalmologic examinations every 3. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine toxicity monitoring Hydroxychloroquine Plaquenil Toxicity and., Hydroxychloroquine DermNet NZ Chloroquine chemoHydroxychloroquine and herb combinationGive brand names of chloroquineAlternative to plaquenil for lupus Annual screening may be commenced before 5 years of treatment if additional risk factors for retinal toxicity exist, such as concomitant tamoxifen therapy, impaired renal function eGFR less than 60 mL/minute/1.73 m 2 or high-dose therapy greater than 5 mg/kg/day of hydroxychloroquine sulfate. HYDROXYCHLOROQUINE SULFATE Drug BNF content published by NICE. RETINA PEARLS Monitoring for Hydroxychloroquine Retinal.. Monitoring for retinal toxicity in patients taking hydroxychloroquine.. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Hydroxychloroquine HCQ is an anti-malarial medication that has in recent times been utilized as treatment for a variety of autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, and other inflammatory and dermatologic conditions. Retinal toxicity from HCQ, and its analog, chloroquine, has been recognized for many years.2,3 By some estimates, in the United. Ensure baseline monitoring of full blood count, biochemical profile ophthalmological examination and muscle function. Discuss how the patient / carer can be aware of possible signs hydroxychloroquine toxicity or intolerance Provide written instruction to the GP for initiation and escalation of hydroxychloroquine.