Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Caffeine and plaquenil Hydroxychloroquine and white spots on skin Our results regarding blood hydroxychloroquine and desethylchloroquine concentrations in 223 treated patients did not show any significant relationship between cigarette smoking and hydroxychloroquine or desethylchloroquine concentrations. This is a strong argument against a direct effect of smoking on hydroxychloroquine metabolism. Proton pump inhibitor drug interactions can happen with medicines ranging from aspirin to cancer drugs. People should be aware of how proton pump inhibitors interact with other drugs they take. PPIs alter the pH of the stomach. The pH is a measure of stomach acidity. Drug interactions are reported among people who take Plaquenil and Coumadin together. This study is created by eHealthMe based on reports of 920 people who take Plaquenil and Coumadin from Food and Drug Administration FDA, and is updated regularly. On Nov, 07, 2019 920 people who take Plaquenil, Coumadin are studied. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil and coumadin interaction Acetaminophen and Warfarin The Forgotten Interaction, Proton Pump Inhibitor PPI Interactions Drugs, Foods & Drinks Chloroquine causes itch mechanismPlaquenil 200mg side effectsDoes hydroxychloroquine thin the blood Plenty of people take both Plaquenil and Coumadin without problems but there definitely are therapeutic problems from time to time. Raglet's advice is spot on. I don;t know of any reason not to stuff yourself with Vitamin K rich foodstuffs, just mention to your doctors that you are doing this- I have no idea how long it takes to reduce the anti. Plaquenil Is Thinning My Blood Lupus Forums at The Lupus Site. Plaquenil and Coumadin drug interactions - eHealthMe. Plaquenil Oral Interactions with Other Medication. Digoxin, cyclosporine, and certain beta blockers may cause drug interactions with hydroxychloroquine. This eMedTV segment explores what may happen if these drugs are taken with hydroxychloroquine and lists other drugs that may cause an interaction. Hydroxychloroquine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully. I'm on Plaquenil for leukocytoclastic vasculitis among other autoimmune problems. Is this why Plaquenil is thought to be effective in treating this? I keep hearing about the vascular problems with the virus and autoimmune drug intervention, but I'm confused about the intent behind the medicine.