Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and sarcoidosis Plaquenil and dry mouth May 23, 2019 Drusen are yellow deposits under the retina. Drusen are made up of lipids, a fatty protein. Drusen are made up of lipids, a fatty protein. Drusen likely do not cause age-related macular degeneration AMD. Find information about common, infrequent and rare side effects of Plaquenil Oral. Drusen Deposits in the Eye Drusen are small yellow or white deposits that form in the retina or on the optic nerve head. They are accumulations of extracellular material that build up in the eye. The detection of a few drusen is normal with aging eyes, with most people over the age of 40 having at least some drusen. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil drusrn deposits Recommendations on Screening for Chloroquine and., Common and Rare Side Effects for Plaquenil Oral Plaquenil side effects insomnia The drusen-like deposits were located in a ring-shaped distribution between the retinal pigment epithelium and Bruch's membrane, with the majority of eyes having macular sparing. In patients with glomerulonephritis, the drusen-like deposits were more numerous than in those systemic lupus erythematosus patients without renal involvement. Drusen-Like Deposits Common in Young Adults With Systemic.. Drusen Deposits in the Eye -. Plaquenil Side Effects Common, Severe, Long Term -. Subretinal Drusenoid Deposits In Non-Neovascular Age-Related Macular Degeneration Morphology, Prevalence, Topography, And Biogenesis Model. Luibl V, Isas JM, Kayed R, et al. Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers. A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to. Sep 04, 2007 Well I had my regular ophthalmology appointment today and the doc said he sees drusen in my eye. He said that its a pre-sign to macular degeneration which can lead to partial blindness. Because of my age I'll be 32 this month it is very rare. Thing is he didn't see it back in January when I went for my baseline appt before starting Plaq.