Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take chloroquine with all of your drugs and health problems. Hydroxychloroquine plaquenil rheumatoid arthritis Does plaquenil cause coughing Fda approval chloroquine-primaquine With Chloroquine trial and suggest a clinical beneﬁt of the addition of CQ to antiestrogen therapy for the treatment of ERþ breast cancer. Furthermore, this study predicts a more modest result for combining Faslodex and chloroquine-based therapies for prevention and/or treatment of breast cancer. Chloroquine Inhibits Breast Cancer Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy. Maycotte P1, Aryal S, Cummings CT, Thorburn J, Morgan MJ, Thorburn A. Chloroquine CQ is a 4-aminoquinoline drug used for the treatment of diverse diseases. Chloroquine's potential chemosensitizing and radiosensitizing activities in cancer may be related to its inhibition of autophagy, a cellular mechanism involving lysosomal degradation that minimizes the production of reactive oxygen species ROS related to tumor reoxygenation and tumor exposure to chemotherapeutic agents and radiation. For all uses of chloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Chloroquine breast cancer Roles of autophagy in breast cancer treatment Target, bystander or., The Chloroquine Story in Cancer Continues In the Pipeline Plaquenil weight gain lupusTaking plaquenil and carafateWill plaquenil help with memoryShared care guidelines hydroxychloroquinePlaquenil eye risks There is a growing evidence that antimalarial chloroquine could be re-purposed for cancer treatment. A dozen of clinical trials have been initiated within the past 10 years to test the potential of chloroquine as an adjuvant treatment for therapy–refractory cancers including glioblastoma, one of the most aggressive human cancers. While there is considerable evidence for the efficacy and. Frontiers Re-purposing Chloroquine for Glioblastoma Potential Merits.. NCI Drug Dictionary - National Cancer Institute. Dissecting pharmacological effects of chloroquine in cancer treatment.. Strange as it may sound, but it is true. Yes, this is what a group of researchers from Harvard Medical School recently reported in a reputed journal. I believe most of us especially those living in India and Africa, are well aware of Chloroquine, which is known as one of the most widely and successfully used first generation anti-malarial drug. Autophagy-addicted breast cancers killed by anti-malaria drug, chloroquine by University of Colorado Denver The process of autophagy cleans cells – they wrap up the bad stuff and then dispose of it. In fact, the researchers believe that chloroquine stands a good chance as a routine drug taken by women on a yearly basis to prevent breast cancer. That, of course, will only happen after a long series of clinical trials. The PINC trial joins two other clinical trials involving breast cancer led by George Mason researchers.