So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Maculopathy from plaquenil Opthamologist plaquenil eye exam montgomery al Effects of plaquenil and alcohol Plaquenil and sulfasalazine combination Do you still have joint and muscle pain on plaquenil? I've been on plaquenil for 6 months now and I still have significant joint pain! I can't say that the drug has helped at all, but it is difficult to compare todays pain with that of 6 months ago. Aug 26, 2016 Plaquenil is supposed to stay in your system for 1-2 months after you stop taking it. Try to rest, stay hydrated and away from sick ppl for now and hopefully you will not have any issues I love plaquenil. I would marry it if it was legal to do so. Took me 'bout nine months or so before I noticed it doing anything. Mostly I find it helps for fatigue rather than joint pain for me anywho. This time round I've been on it for almost 2 years and wouldn't give it up. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Joint pain after stopping plaquenil Discontinued Plaquenil.other options?, Stopping Plaquenil - General Discussion - Life With Lupus Plaquenil purchase onlinePlaquenil side effects vaginalChloroquine invitrogenReticulocytes chloroquineLiterature review of chloroquine syrup You mentioned that you didn't have the joint issues and didn't know why you were taking Plaquenil? Well, so you DON'T have the aches later. Plaquenil slows the progression of the disease. Go ahead and call the Rhuemy now, or just wait until Monday, if you have had this for a few weeks anyway. Can you quit plaquenil cold turkey, or have to wean. Plaquenil -. Will you have Joint pain with Plaquenil - eHealthMe. Nov 12, 2009 I started taking plaquenil seven years ago and i feel that it has really helped me, I feel much better. I know that it helps with the joint pain but it also is bad for other parts of your body. Lately i feel like my eye sight is getting really bad. I feel it can help you but it can also hurt you. I have stopped taking this medication one week ago. Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Specifically, anti-malarial medications have shown to improve muscle and joint pain, skin rashes, pericarditis inflammation of the lining of the heart, pleuritis inflammation of the lining of the lung, and other lupus symptoms such as fatigue and fever.