I was diagnosed with discoid lupus 18 years ago and was prescribed Plaquenil, which I have taken since then. In October 2012, I was also diagnosed with Sjogrens Syndrome but, as I was already taking Plaquenil, was advised the treatment was the same for Sjogrens. Does plaquenil make an infection worse Compare sulfasalazine to plaquenil Ocular follow-up in regards to hydroxychloroquine White blood cell count decreased is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have High blood pressure. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Nov 16, 2018 A low platelet count is a blood disorder that can sometimes be serious. This article looks at platelets and their role within the body. Find out about the many possible causes of a low count. From research I have done online, I gather that low white cell count can also be a symptom of the Sjogrens in itself. At a recent medical with my doctor, blood tests were taken and I had a call a couple of days later telling me to stop taking g Plaquenil immediately as I have a very low white cell count and that it is sometimes a side effect of Plaquenil. Plaquenil and low white blood count What does a Low White Blood Cell Count Indicate?, Hydroxychloroquine Plaquenil Side Effects & Dosage for. Plaquenil et le soleil White blood cell count decreased is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have High blood pressure Will you have White blood cell count decreased with Plaquenil.. Low platelet count thrombocytopenia Causes, treatment, and.. Common and Rare Side Effects for Hydroxychloroquine Oral. My Absolute Neutrophils good indicator of immune system function didn't get suppressed to a NORMAL range until I increased the Plaquenil to 600mg/day while still taking the Prednisone. In addition, my white blood cell count was still within a normal range. Expand. My rheumy has never mentioned that Plaquenil can cause a low white blood cell count, this is strange as mine has always been between 1.0 and 2.0, but mostly hovers around 1.2. Logged grammad97 I was recently diagnosed with Lupus Aprli 2011 and was started on Plaquenil in May 2010 200 mg X daily. Although my white blood count has always been in the low end of normal low 4's it has been dropping recently. Latest test done at hematologist showed that my count was 2.2.