Controlled studies in pregnant women show no evidence of fetal risk. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. Animal studies show risk and human studies not available or neither animal nor human studies done. Contact the applicable plan provider for the most current information. D: Use in LIFE-THREATENING emergencies when no safer drug available. Cheaper alternative to plaquenil Ati hydroxychloroquine For oral dosage form tablets For prevention of malaria Adults—500 milligrams mg once a week on the same day of each week starting 2 weeks before traveling to an area where malaria occurs, and continued for 8 weeks after leaving the area. Children—Dose is based on body weight and must be determined by your doctor. Apr 15, 2002 Chloroquine is the drug of choice for people who travel to these areas; however, resistance to chloroquine is now widespread in all areas of the world where malaria is endemic, but it is still an. Both adults and children should take one dose of chloroquine per week starting at least 1 week before. traveling to the area where malaria transmission occurs. They should take one dose per week while there, and for 4 consecutive weeks after leaving. The weekly dosage for adults is 300mg base 500mg salt. Active against erythrocytic forms of Plasmodium vivax & P. malariae and most strains of Plasmodium falciparum Precise mechanism not known Bioavailability: ~89% Peak plasma time: 1-2 hr Distributed widely in body tissues (eg, eyes, heart, kidneys, liver, lungs) where retention prolonged; crosses placenta; enters breast milk Partially in liver Half-life: 3-5 days Excretion: urine (~70% as unchanged drug); acidification of urine increases elimination Small amounts may be present in urine months following discontinuation of therapy The above information is provided for general informational and educational purposes only. Chloroquine for malaria prophylaxis dosing Chloroquine Phosphate chloroquine phosphate dose., Recommended Malaria Prophylaxis for Travelers Plaquenil co kontrolowacChloroquin for aquariumPlaquenil et piluleDoes plaquenil cause coughing The pharmacokinetics of chloroquine were studied in healthy volunteers who received one of three different multiple-dose regimens for 3 weeks once weekly 300 mg, twice weekly 200 mg and once daily 50 mg chloroquine. Plasma concentrations of chloroquine and metabolites were determined by h.p.l.c. with fluorescence detection. The pharmacokinetics of three multiple dose regimens of.. Medicines for the Prevention of Malaria While Traveling.. Aralen Chloroquine Uses, Dosage, Side Effects.. Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. The standard chloroquine dose for treating malaria in adults is a one-time loading dose of 1000 mg, followed by 500 mg in six to eight hours. Then 500 mg is taken once a day for two more days. The standard dosage for malaria treatment in children is based on the child's weight. Chloroquine phosphate or hydroxychloroquine sulfate Plaquenil can be used for prevention of malaria only in destinations where chloroquine resistance is not present see Chapter 2, Yellow Fever Vaccine & Malaria Prophylaxis Information, by Country. Prophylaxis should begin 1–2 weeks before travel to malarious areas.