This study is created by e Health Me based on reports of 57,706 people who have side effects when taking Plaquenil from Food and Drug Administration (FDA), and is updated regularly. On e Health Me, you can evaluate side effects and drug interactions from 16 million FDA reports. Plaquenil cause fatigue Can plaquenil help skin cancer Headache inability to move the eyes increased blinking or spasms of the eyelid joint or muscle pain large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, and sex organs loss of hearing lower back or side pain noisy breathing painful or difficult urination red irritated eyes Then rest in a darkened room. Remember also to keep hydrated.being slightly dehydrated can trigger headaches and migraines. I still take Plaquenil and have been on them since 2006. The migraines are no better or worse than before. So in my experience, the Plaquenil is not a problem for me. Confused whether the headaches are lupus headaches vs migraines or both? Understanding the causes and symptoms can help you decide the right treatment options. #LupusWarriors might experience the dreaded lupus fog bringing the mind and body often to a confused state and difficulty remembering potentially crucial parts of their life. You can also discuss your drugs with qualified professionals to ensure drugs are working to improve your health. The study is based on hydroxychloroquine sulfate (the active ingredients of Plaquenil) and Plaquenil (the brand name). Headache (pain in head) has been reported by people with multiple sclerosis, rheumatoid arthritis, high blood pressure, depression, pain. The results are personalized to your gender and age (0-99 ). Plaquenil and headaches Plaquenil and headaches DailyStrength, Migraines and plaquenil. Connection? DailyStrength Hydroxychloroquine monitoring requirementsHydroxychloroquine prophylaxisGeneric plaquenil gg 620 Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Lupus Headaches vs Migraines—What's the Difference.. Plaquenil headache. Lupus Forums at The Lupus Site. When I started the Plaquenil, I had headache and migranes also. I'm on the same dosage too. I took mine with food or milk, or with yogurt. That seemed to help, but I stopped having the headaches after several weeks, it just took my body some time to get use to it I think. I even lost some weight. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. PLAQUENIL brand-name is fantastic, however the generic Hydroxychloroquine is awful. After another two months on the drug I experienced serious headaches and my Rhumatologist reduced the dose.