Please review the following URL and make sure that it is spelled correctly. Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). Plaquenil hydroxychloroquine ocd Chloroquine and hearing loss Hydroxychloroquine pericarditis Plaquenil and juvenile arthritis blue eyes Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Immune system disorder is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain I doubt it is the Plaquenil affecting your immune system, but the actual Lupus itself as it can affects the white blood cells and lower them so we get every infection going. You need to speak to your rheumy for more clarification in your case. It may prevent joint damage and reduce the risk of long-term disability. It can decrease the pain and swelling of arthritis. Plaquenil immune system Plaquenil and lowered immune system - Sjogren's World, Will you have Immune system disorder with Plaquenil. What happens when you quit taking plaquenil In 2003, a novel mechanism was described wherein hydroxychloroquine inhibits stimulation of the toll-like receptor TLR 9 family receptors. TLRs are cellular receptors for microbial products that induce inflammatory responses through activation of the innate immune system. Hydroxychloroquine - Wikipedia. Plaquenil and immune system Lupus Forums at The Lupus Site. Hydroxychloroquine Plaquenil. It is not well understood how Plaquenil helps treat autoimmune diseases like lupus and many types of arthritis. It is thought that Plaquenil interferes with how cells in the immune system communicate with each other. There is evidence that hydroxychloroquine may interfere with communication between cells in the immune system. This action suppresses the normally overactive immune response in lupus patients which may explain one reason Plaquenil works so well for those suffering with lupus. Plaquenil changes the way your immune system works. In some kinds of lupus, your immune system attacks your body instead of protecting it. Plaquenil tries to quiet or slow down the immune system. How do you take Plaquenil? You take Plaquenil as a pill 1 or 2 times a day. Take the pills with food or milk.