Is hydroxychloroquine safe to take during pregnancy

Discussion in 'Canadian Pharmacies Online' started by Vandamize, 01-Mar-2020.

  1. aviafm User

    Is hydroxychloroquine safe to take during pregnancy


    Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.

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    The role of hydroxychloroquine HCQ for achieving this control is now recognized. Several studies demonstrate that patients with SLE who continue HCQ during pregnancy have decreased flares and improved pregnancy outcomes, including longer fetal gestation and infants with higher birth weight3,4. In early pregnancy is essential to reduce these risks. Therapy may include low dose prednisolone 2, azathioprine 5, and /or hydroxychloroquine 6 - 8 as these have proved safe and efficacious in pregnancy 5. Hydroxychloroquine in particular is associated with improved obstetric outcomes in SLE 9. Please discuss this with your doctor before taking this medication. However, hydroxychloroquine has been shown to be safe during pregnancy and breast feeding. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time.

    Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.

    Is hydroxychloroquine safe to take during pregnancy

    Is it safe to take plaquenil while pregnant - What, Treatment of SLE in pregnancy and use of Chloroquine The BMJ

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  4. OBJECTIVE The use of hydroxychloroquine HCQ in pregnancy remains controversial. The recent demonstration that HCQ passes across the placenta, with cord blood concentrations nearly identical to those found in maternal blood, emphasizes the need for careful evaluation of pregnancies in women receiving HCQ.

    • Safety of hydroxychloroquine in pregnant patients with..
    • PATIENT FACT SHEET Hydroxychloroquine Plaquenil.
    • Hydroxychloroquine 'Probably Safe' in Pregnancy MDedge ObGyn.

    Hydroxychloroquine is usually considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known. Talk to your healthcare provider about the risks and benefits of using hydroxychloroquine during pregnancy see Plaquenil and Pregnancy for more information. Use of corticosteroids during pregnancy in patients with RA has been associated with increased risk of premature delivery. Despite these risks, corticosteroids are considered relatively safe throughout pregnancy when given at low doses below 15 mg/day. It does not appear to be safe during pregnancy. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication. Hydroxychloroquine was approved for medical use in the United States in 1955.

     
  5. soykino Well-Known Member

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Hydroxychloroquine Side-effects, uses, time to work What Is Hydroxychloroquine and How Does It Help Arthritis. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis
     
  6. as_ User

    Plaquenil is eigenlijk een middel voor de behandeling van malaria en het voorkómen daarvan. Hydroxychloroquine - Malaria Home Page Hydroxychloroquine Oral Route Before Using - Mayo Clinic Medicines for the Prevention of Malaria While Traveling.
     
  7. Ol4ik Well-Known Member

    New Guidelines on Hydroxychloroquine Dosage - Where Are We. The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity 1. According to these new guidelines, the risk of HCQ retinal toxicity is less than 1 % in the first year of therapy and less than 2 % up to 10 years of therapy.

    Chloroquine And Hydroxychloroquine Toxicity - StatPearls.
     
  8. SniperP User

    Identification of a Lysosomal Pathway That Modulates Glucocorticoid. By inhibiting lysosome function, chloroquine synergistically activated glucocorticoid signaling. Lysosomal inhibition by either bafilomycin A1 an inhibitor of the vacuolar adenosine triphosphatase or knockdown of transcription factor EB TFEB, a master activator of lysosomal biogenesis mimicked the effects of chloroquine. The

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