The advice represents a significant shift in practice and results in a substantial additional workload for ophthalmology services to undertake and interpret retinal imaging. In follow up to the BSR guidelines, and in response to the recognition of the increasing number of patients identified with advanced HCQ retinopathy [2, 3], the Royal College of Ophthalmologists (RCOphth) have now published their own, more detailed, recommendations; these provide additional clarity to the BSR guidelines regarding the diagnostic tests required and suggested monitoring schedules . Chloroquine tlr9 inhibitor Lyrica and plaquenil Chloroquine volume of distribution Aralen buy online RCOphth guideline Hydroxychloroquine and Chloroquine Retinopathy NEW screening recommendations February 2018 2 March 2018. The new guideline on screening for hydroxychloroquine and chloroquine retinopathy is written in response to evidence from the United States that shows that hydroxychloroquine retinopathy is more common than previously recognised. The Royal College of Ophthalmologists RCOpth published guidance on hydroxychloroquine and chloroquine retinopathy screening in 2018. The guidance recommends that all patients planning to take hydroxychloroquine long term i.e. more than five years should have an OCT scan within 12 months preferably within six months of starting therapy and annual screening following five years of treatment. The Royal College of Ophthalmologists guidance identifies the requirements to introduce systematic screening for hydroxychloroquine retinopathy and reduce inequality in access, establish standardised screening schedules and confirmation of best practice. During treatment, it recommends ‘annual eye assessment (ideally including optical coherence tomography) if treatment is continued for 5 years’ . The current BSR guidelines state ‘Patients should have baseline formal ophthalmic examination, ideally including objective retinal assessment for example using optical coherence tomography, within 1 year of commencing an antimalarial drug’ . Royal college of ophthalmologists hydroxychloroquine Hydroxychloroquine toxicity Eye News, Statement hydroxychloroquine and chloroquine retinopathy screening. Plaquenil similarPlaquenil tegen malariaLupus flare while on plaquenilWhats the dosage that causes plaquenil toxicityPlaquenil side effects tired Hydroxychloroquine is used routinely in the early arthritis pathway for new onset rheumatoid arthritis alongside methotrexate and is also used in connective tissue diseases. It is normally initiated by rheumatologists or dermatologists with prescribing being shared with GPs after a period of stabilisation. Hydroxychloroquine and Retinal Screening. HCQ Screening. HYDROXYCHLOROQUINE SULFATE Drug BNF content published by NICE. The Royal College of Ophthalmologists. Hydroxychloroquine and Chloroquine Retinopathy Recommendations on Screening. Shah CP, et al. Expanded spectral domain-OCT findings in the early. The Royal College of Ophthalmologists recommended screening for Hydroxychloroquine and Chloroquine Retinopathy in February 2018. Due to the different funding mechanisms in Scotland, the additional Ophthalmology capacity required to allow implementation can only be achieved to the detriment of the existing care of Screening may not “prevent” damage, but if conducted properly it enables the detection of toxicity before vision is significantly affected. The Royal College of Ophthalmologists published guidelines on “Hydroxychloroquine and Chloroquine Retinopathy Recommendations on Screening” in February 2018.