Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Plaquenil fever Plaquenil to treat skin rash What category is plaquenil Does plaquenil cause coughing The Hydroxychloroquine Dosing Calculator calculates appropriate daily dose of hydroxychloroquine. is on a dose that exceeds 5 mg/kg/day of real body weight, the. He pointed out that these findings have been validated in several studies using other patient populations. He concluded that the risk is very real of developing retinal toxicity with prolonged use of hydroxychloroquine. The dose, duration, presence of renal disease and use of other drugs such as tamoxifen all contribute to the increased risk. Chloroquine is often part of a multi-drug regimen with other anti-parasitic medications. A cumulative dose of over 460 g or a daily dose of 2.3 mg/kg body weight/day is high risk. The latest studies show that using the patient's real weight instead of ideal weight correlates better with safe dosing. Chloroquine is rarely an option for rheumatic. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Hydroxychloroquine real weight safe dose Recommendations on Screening for Chloroquine and., The 2018 ACR Great Debate Hydroxychloroquine Dosing for SLE Rates of plaquenil toxicityCcca plaquenilHow good is plaquenil for diabetesChloroquine gbmPlaquenil tamoxifen toxic symptoms There is a small risk that hydroxychloroquine can damage your retina part of the eye, and this increases with long-term use and higher dosage. Your doctor will advise you on a safe dose to take according to your weight, and you will need to have regular monitoring of your eyes. Hydroxychloroquine Side-effects, uses, time to work. Chloroquine And Hydroxychloroquine Toxicity - StatPearls.. Plaquenil Dosage Guide -. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Nov 09, 2018 Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.