Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine resistant malaria treatment in children Chloroquine prices Weiggt gain tryibg to get off plaquenil I don't know for sure if it is the plaquenil or other meds but my rheumy seems to have my inflammation/stiffness under pretty good control. Been taking plaquenil and arava for about a year. Just rediced plaquenil from one tablet twice a day to one tablet once a day. I also take Cimzia injections bi-weekly but that has only been for about 6 months. I have been on Plaquenil for years. It has not helped me with fatigue. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time. I also take Tramadol for pain and now Indomethicin has been added to the mix to help with stiffness. Plaquenil stays in your body for about 3 months. If you must stop it, it will take a while for the side effects to go away. You should have an eye examination every year to prevent a very rare but serious eye problem. Less than one person in 5,000 develops the problem. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Will plaquenil take joint swelling away Will you have Joint pain with Plaquenil - eHealthMe, Plaquenil for fatigue and pain DailyStrength What does chloroquine treatHumblefish chloroquine I am glad I switched to the cymbalta, perhaps the combination of it and 400 mg of plaquenil will work for me. It seemed to help the swelling in my hands too. I had an uncle with RA whose been dead for years now but it was before all the better drugs came out and he was so crippled up. It was so very sad. I don't know how he stood it. What next if plaquenil doesn't work? -. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. Plaquenil - Uses, Side Effects, Interactions.. If you miss a dose, take it as soon as you remember. If it is very near the time of the next dose, skip the missed dose and continue with your normal dosing schedule. Do not double dose at one time to catch up. Plaquenil should be stored away from light and moisture and at room temperature up to 86 degrees F. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. However, these are all so minor when I compare to the good plaquenil is doing in my life. I don't want to have my joints deterioriate and not be able to do the things I love. I don't want my diseases to affect my internal organs and take my life away. Plaquenil can save and extend your life. Please consider taking your doctor's advice.