I had some of the usual problems with the upset stomach at the beginning but it got better with time. Over the last 8-10 weeks I have noticed that I have been getting very dark circles under my eyes which starts at the inner corner of my eye. Can i take plaquenil and ibuprofen Plaquenil for arthritis pain Hydroxychloroquine sulfate dosage How does plaquenil treat lupus Common, nonocular, side effects of chloroquine and hydroxychloroquine include pruritus, headaches, dizziness, and gastrointestinal upset. Less frequent side effects include discoloration of the oral cavity, nails, skin and hair and rash. HCQ myopathy is uncommon and presents with proximal muscle weakness and rarely ventilatory failure. Nonmelanic pigmentation occurs when the nail matrix extracts the drug and stores it in the nail, or the drug deposits in the nail or subungual area. The nail may turn blue, brown, or gray, depending on the drug, and the color will grow out as the nail does. 1,20,21; Irritant or allergic reactions. Topical agents sometimes cause nail changes. This Home Depot guide explains all that you need to know about Nails, Design, Types and Techniques to accomplish the high-quality work you expect from yourself. I thought it was because I was not doing very well for a couple of weeks.... When I looked closer the skin is a little red with a bluish black color like a bruise. Gray nails and plaquenil Color of Fingernails and Toenails Health Indicator Chart., Drug-Induced Nail Changes Counting to 10 Joint task force-bravo chloroquine 1989 Nail symptoms explained Signs you shouldn't ignore. What do ridges on nails, white spots mean? Your nails can signal everything from lung conditions to anemia. Nail symptoms explained Signs you shouldn't ignore. Finishing Nails - Nails - The Home Depot. Lichen Planus in Adults Condition, Treatments, and Pictures - Overview.. Skin pigmentation related to use of hydroxychloroquine starts out as a yellow brown to slate gray or black pigmentation on many areas of the body - especially the front of the shins but also the face, forearms, mouth mucosa essentially hard palace and gingivae and nail beds. How common is it? Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.