It has been suggested I might begin taking this after my next visit to the Rheumatology Consultant, and he has given me a very brief leaflet on it to consider. Its effects took about 8 weeks to get in my system . Laura I have been taking this for years - just had my dose upped. Hi I have been taking hydroxy for a few years I found it took a bit off an edge of some of my symptoms primarily the joint pain. Have found it does ease joint pain and has reduced my facial lesions. Chloroquine diphosphate 25 μm Malarone and plaquenil Hydroxychloroquine 200 mg side effects Jan 16, 2009 Prednisone often causes heartburn and like everyone said NSAIDs can cause stomach pain, ulcers, and even bleeding. Because I take prednisone and celebrex daily, I also have to take Nexium which is a prescription antacid. I really hate nausea so I keep prescription phenegren on hand. I know it sucks to take extra medication to fight side effects, but it's better than getting an ulcer. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Hi, I JUst wanted to let you know that Plaquenil, and other lupus meds can be rough on your stomach.so in the beginning than long term. My doctor reccomended that I eat 100 calories at least prior to taking Plaquenil and Naproxen. I was prett nauseous the frist 2 weeks on these meds, but over time it diminished. If it keeps me off the steroids I'll carry on using it. The main thing it helped for me was feeling tired all the time. There are rare side effects on the eyes, I have a bit of double vision now and its been corrected with prism lenses in my glasses. Experienced nausea in first few weeks but soon eased. Plaquenil stomach ulcer Will you have Pressure ulcer with Plaquenil - eHealthMe, Hydroxychloroquine Side Effects, Dosage, Uses, and More What is the mode of action of chloroquine Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil and stomach issues." Lupus Community - Support.. Plaquenil Withdrawal – Life As An Anomaly. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can. Aug 02, 2010 plaquenil, pain, nausea/vomiting, gerd, ulcer. Added Mobic is also a arthritis drug,ive taken that for years without side effect im more concerned about an answer about the plaquenel. Stomach cramps Again these symptoms are very non specific and depend on the finding of a raised serum calcium level. Treatment depends on the severity of the condition. Plaquenil is one of the most frequently used preventative measures for the issue. Plaquenil lowers the levels of 1,25D and therefore calcium in the blood at a moderate rate.