But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Read more Anxiety over potential eye problems with Hydroxychloroquine is completely unwarranted if the dose is kept below 6mg/kg (2.2lbs) of body weight. Read more See 1 more doctor answer It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Read more Results are very good, particulary when used alone and better with methotrexate. How long does it take plaquenil to damage bones Plaquenil pregnancy otis Kikuchi-fujimoto disease hydroxychloroquine as a treatment Can hydroxychloroquine be sold as brand name Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Drug Interactions A total of 329 drugs are known to interact with Plaquenil 58 major drug interactions 158 brand and generic names 266 moderate drug interactions 1022 brand and generic names 5 minor drug interactions 23 brand and generic names A total of 565 drugs are known to interact with methotrexate Substitutes and alternatives to Plaquenil hydroxychloroquine for uses like Rheumatoid arthritis, Lupus and Malaria Chloroquine can be substituted for Plaquenil but only in limited circumstances. Please provide more detailed information if you want a more specific answer. Read more See 1 more doctor answer Depends on what you are being treated for.... Read more While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. So other meds like Imuran and Cell Cept (mycophenolate mofetil) also reduce flares, but also increases infection. Read more It depends why you are taking Plaquenil in the first place. Apart from some stomach quiziies, I have never stopped this drug, as long as it demonstrated it is working. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. Is there a natural drug substitute for plaquenil Natural Lupus Treatment for Symptoms and Management - Dr. Axe, Plaquenil Compared to Alternatives - Hydroxychloroquine chronic fatigueChloroquine sigma autophagy Glenn Frey's death, tied in part to rheumatoid arthritis medications he was taking, is a 'wake-up call' about the dangers of powerful drugs used to treat the condition, a top doc says. It should push arthritis patients and their doctors to seek out safer available alternatives. Safe, Natural Alternatives to Arthritis Drugs Top Doc.. Plaquenil hydroxychloroquine Alternatives & Similar Drugs.. Is there an alternative to Plaquenil? - Sjogren's World. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Namey on plaquenil substitute Plaquenil is also known as hydroxychloroquine, so the parent drug Chloroquine can be substituted. But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Mar 05, 2010 provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Dec 29, 2004 I'm still searching for that magic "all natural" replacement since I cannot tolerate plaquenil. The stomach, liver & eye complications are too great to bear. and that's at the lowest, lowest dose. Anyway, guess I need to get into some deeper research about exactly what this drug does, and see if there's an herb out there that may help.