It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Chloroquine toxicity Skin cancer side effect of plaquenil Plaquenil and oxymetazoline hydrochloride Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Hydroxychloroquine sulfate is indicated for the suppressive treatment and treatment of acute attacks of malaria due to Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is also indicated for the treatment of discoid and systemic lupus erythematosus and rheumatoid arthritis. Jan 01, 2020 Plaquenil - Clinical Pharmacology Pharmacokinetics Following a single 200 mg oral dose of Plaquenil to healthy male volunteers, the mean peak blood concentration of hydroxychloroquine was 129.6 ng/mL, reached in 3.26 hours with a half-life of 537 hours 22.4 days. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine prescribing information HYDROXYCHLOROQUINE SULFATE Drug BNF content published by NICE, HYDROXYCHLOROQUINE - Hydroxychloroquine sulfate How do i know if i'm allergic to hydroxychloroquineWill plaquenil help cancerMethotrexate and hydroxychloroquine Prescribing framework for Hydroxychloroquine Date approved by the HERPCMarch 2014 Review dateSeptember 2019 Page 4 of 4 10. Initiation Assess the patient following referral by GP Recommend appropriate treatment to the GP and send shared care framework. Carry out baseline full blood count, biochemical profile. Prescribing Framework for Hydroxychloroquine in Rheumatic and.. Plaquenil - FDA prescribing information, side effects and uses. Hydroxychloroquine - Side Effects, Dosage, Interactions.. One tablet of 200 mg of hydroxychloroquine sulfate is equivalent to 155 mg base. Malaria Suppression In adults, 400 mg =310 mg base on exactly the same day of each week. In infants and children, the weekly suppressive dosage is 5 mg, calculated as base, per kg of body weight, but should not exceed the adult dose regardless of weight. Long-term ≥5 years treatment with hydroxychloroquine include daily doses greater than 6.5 mg/kg 5 mg/kg base of actual body weight, subnormal glomerular filtration rate, durations of use longer than five years, and concurrent treatment with tamoxifen citrate. Hydroxychloroquine can be taken with a glass of milk or a meal to decrease nausea. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take hydroxychloroquine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.