It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Chloroquine sulfa allergy Does plaquenil contain steroids Hydroxy chloroquine rheumatoid arthritis pregnancy Chloroquine and primaquine side effects Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. Plaquenil. Uses. Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of. Side Effects. Precautions. Interactions. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Plaquenil kidneys Hydroxychloroquine Oral Route Description and Brand., Plaquenil Oral Uses, Side Effects, Interactions. Brand name plaquenil better than genericLa hi hydroxychloroquineManufacturer coupons for hydroxychloroquine Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Hydroxychloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria. Hydroxychloroquine Oral Route Description and Brand Names.. Hydroxychloroquine Plaquenil. Plaquenil hydroxychloroquine sulfate dosing, indications.. Renal clearance in rheumatoid arthritis patients taking PLAQUENIL for at least six months seemed to be similar to that of the single dose studies in volunteers, suggesting that no change occurs with chronic dosing. Range for renal clearance of unchanged drug was approximately 16 to 30% and did not correlate with creatinine clearance; therefore, a dosage adjustment is not required for patients with renal impairment. Plaquenil increases the pH of lysosomes and impairs complement-dependent antigen-antibody reactions. It also inhibits the chemotaxis of eosinophils and locomotion of neutrophils. SUMMARY OF EVIDENCE in development A total of 2619 patients without previous kidney diseases were diagnosed with rheumatoid arthritis in the LHID2005 between January 1, 2000 and December 31, 2013 Figure 1. Of them, 1212 patients were hydroxychloroquine users, and 1407 were nonusers.