While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Hi, I was diagnosed with RA and was put on sulfa, my rheumy tried adding mtx but i had awful side effects so am now on hydroxychloroquine and sulfa..this combination worked for anyone? Hi I've been on this combination for a few months and unfortunately it hasn't worked for me - but that's not to say it won't for you, we are all different in how we react to drugs. Sulphasalasine was helpful in my case but took 12 weeks to kick in. How to take plaquenil without getting nauseous Plaquenil and dizziness Chloroquine neuropathy Plaquenil costco Reviews and ratings for sulfasalazine when used in the treatment of rheumatoid arthritis. 51 reviews submitted. User Reviews for Sulfasalazine to treat Rheumatoid Arthritis. "I started taking sulfasalazine SZS with Plaquenil 2 months ago for RA. Immediately felt dizzy, confused, nosebleed and depression and also severe vision changes. This article primarily covers the author's experience with the use of the combination of methotrexate MTX, sulfasalazine SSZ, and hydroxychloroquine HCQ to treat patients with rheumatoid arthritis RA. It can decrease the pain and swelling of arthritis, prevent joint damage, and reduce the risk of long-term disability. Sulfasalazine is in a type of sulfa drug. You should not take it if you have a sulfa allergy. Sulfasalazine is used in the treatment of rheumatoid arthritis RA, inflammatory bowel disease, and some other autoimmune conditions. I'm about to start MTX & am hoping that I wont have side effects with that! The side effects of the methotrexate for me were horrendous (chronic chest infections) and I'm now asthmatic as a result. I've stopped Sulfa as I was experiencing a bad taste & smell, which may be caused by sulfa. After a while it wasn't as effective and I too was prescribed methotrexate alongside. Sulfasalazine and hydroxychloroquine rheumatoid arthritis RA and Hydroxychloroquine How Effective is it for Rheumatoid., TRIPLE THERAPY WITH METHOTREXATE, SULFASALAZINE, AND. Baseline eye exam plaquenilChloroquine mitophagyMethotrexate and plaquenilSides effects of hydroxychloroquinePlaquenil mg kg eyewiki Although rheumatoid arthritis is generally an inflammatory process of the synovium, structural or mechanical derangement is a frequent cause of pain or loss of joint function. Pain and joint mobility may be improved by a surgical approach. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Sulfasalazine Azulfidine. Treatments for Rheumatoid Arthritis. Background/Purpose The combination of methotrexate MTX, sulfasalazine SSZ and hydroxychloroquine HCQ triple therapy is a highly effective and well-tolerated treatment in rheumatoid arthritis RA. While MTX is the cornerstone of most successful combination therapies, not all patients are candidates for, or tolerate, MTX. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. O'Dell JR, Leff R, Paulsen G, et al. Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications results of a two-year, randomized, double-blind, placebo-controlled trial.