Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Ic hydroxychloroquine Can you take plaquenil while pregnant Dosage of plaquenil for sjogren& 39 Does famotidine interfere with plaquenil Methotrexate in combination with other DMARDs is not superior to methotrexate alone for remission induction with moderate-to-high-dose glucocorticoid bridging in early rheumatoid arthritis after 16 weeks of treatment the CareRA trial. I am on both methotrexate and plaquenil. I have been on plaquenil for over a year and a half and methotrexate since September. I have had no side effects from either one. I get my eyes checked every six months and I am now at once a month on blood work for my liver enzymes used to be every 2 weeks. Mar 24, 2011 no methotrexate doesn't always mean your hair will fall out or thin but some of the side effects are scary, but before you an progress onto other meds methotrexate is mandatory. for me methotreaxte and plaquenil does't work and i' intonate of sulfa so i am started embrel which states you have to have tried 2 of 3 meds and methotrexate is 1 of them. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Does methotrexate work without plaquenil Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Which would you pick and why? - Plaquenil or Methotrexate Can you buy chloroquine over the counterHydroxychloroquine pancreatitisChloroquine tablets asdaH-chloroquine side effectsPlaquenil stomach problems Does Plaquenil actually work for you? I never actually noticed a difference when I was taking Plaquenil long-term. A few years ago, when I stuck to a super healthy diet, I actually noticed a difference in my symptoms, so I stopped taking Plaquenil. Does Plaquenil actually work for you? autoimmunity. What next if plaquenil doesn't work?. Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly?. Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. I was on both for 2 years without a problem, I've stopped taking plaquenil but am still on 20mg methotrexate per week for closer to 3 years now without incident. Yes it's scary to begin with but when your quality of life slowly returns it's all worthwhile. Plaquenil didn't work for me. Methotrexate isn't so bad if you can deal with being stupidly tired and brain foggy one day a week, a day I dub "Methotrexate Hangover Day." Start with either, and keep in mind you may have to try a few different meds before you find one that works.