Hydroxychloroquine for lupus nephritis

Discussion in 'Chloroquine Phosphate 500 Mg' started by Cestoid, 14-Mar-2020.

  1. Ferago Moderator

    Hydroxychloroquine for lupus nephritis


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. -Each dose should be taken with a meal or a glass of milk.

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    Unless contraindicated, hydroxychloroquine should be used as adjunctive therapy in lupus nephritis because of the potential for reduction in rates of disease flare; damage accrual.including. People with systemic lupus erythematosus SLE who stop treatment with hydroxychloroquine less than 12 months after its start are at a higher risk of flares than those who continue using it for at least one year, a study suggests. Patients with membranous lupus nephritis are generally treated with prednisone for 1-3 months, followed by tapering for 1-2 years if a response occurs. If no response occurs, the drug is discontinued. Immunosuppressive drugs are generally not used unless renal function worsens or a proliferative component is present on renal biopsy samples.

    -Concomitant therapy with an 8-aminoquinoline drug is necessary for the radical cure of vivax and malariae malaria. Use: Malaria prophylaxis Acute attack: 800 mg (620 mg base) orally followed in 6 to 8 hours by 400 mg (310 mg base), then 400 mg (310 mg base) once a day for 2 consecutive days; alternatively, a single dose of 800 mg (620 mg base) has also been effective Alternate dosing based on body weight: A total dose representing 25 mg/kg is administered in 3 days, as follows: First dose: 10 mg base/kg (not to exceed 620 mg base) orally Second dose: 5 mg base/kg (not to exceed 310 mg base) orally 6 hours after first dose Third dose: 5 mg base/kg orally 18 hours after second dose Fourth dose: 5 mg base/kg orally 24 hours after third dose Comments: -Each dose should be taken with a meal or a glass of milk.

    Hydroxychloroquine for lupus nephritis

    Hydroxychloroquine in systemic lupus erythematosus - The Lancet, Lupus Patients on Hydroxychloroquine for Less Than 1 Year at.

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  4. A search for systematic reviews of hydroxychloroquine’s efficacy in lupus performed using the Cochrane Library and MEDLINE using the MeSH search terms ‘hydroxychloroquine’ and ‘systemic lupus erythematosus’ only revealed one previous systematic review, though there have been many narrative reviews previously published.

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    Kasitanon N, et al. Hydroxychloroquine use predicts complete renal remission within 12 months among patients treated with mycophenolate mofetil therapy for membranous lupus nephritis. Lupus. 2006;156366-70 Non-proliferative class I, II, V, or VI lupus nephritis PICO question Plaquenil hydroxychloroquine has been used for years as an antimalarial drug. It is also used to combat the symptoms of lupus with minimal side effects Proliferative Lupus Nephritis Treatment With Chloroquine and Hydroxychloroquine The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. S. Federal Government.

     
  5. Military New Member

    the cause of the most lethal human malaria, chloroquine resistance is linked to multiple mutations in Pf CRT, a protein that likely functions as a transporter in the parasite’s digestive vacuole membrane. How is malaria treated and prevented? Facts Leveraging the effects of chloroquine on resistant malaria parasites. Chloroquine, an old malaria drug, may help treat novel.
     
  6. lekoleko Well-Known Member

    My husband has been taking Plaquenil (generic hydroxychloroquine) for almost 2 yrs., under a rheumatologist's care. He became very ill, and was diagnosed w/ viral meningial encephalitis. Hydroxychloroquine Plaquenil Side Effects & Dosage for. Methotrexate vs. Plaquenil - Autoimmune diseases - Inspire Sjogren's syndrome - Symptoms and causes - Mayo Clinic
     
  7. shket1v User

    You can’t lose weight while on Prednisone”you can I had just finished a course of Prednisone for a respiratory problem, and I was aware that, in spite of its undoubted spectacular effectiveness, it would just continue to add to my burgeoning weight problems. After breast cancer, I had put on 15 kg in three years, and that was just part of the continuing steady weight gain over the years.

    Why Prednisone Causes Weight Gain And What To Do About It.
     
  8. Plaquenil Oral Uses, Side Effects, Interactions. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

    Plaquenil Oral Uses, Side Effects, Interactions, Pictures.