Most types of panniculitis have both septal inflammation (early) and lobular inflammation (later). Further classification is based on whether or not there is subcutaneous The outcome depends on the underlying cause of the inflammation. Plaquenil retinopathy visual field Retinal changes with plaquenil Hydroxychloroquine withdrawal When Rosa came to see me for the first time, she brought in a picture of herself before she developed lupus,” Andrew Franks recalls. “I was startled to see a beautiful young woman transformed so drastically. Her form of skin lupus, known as lupus profundus, or panniculitis, causes darkening of the skin and loss of the underlying fat. Subcutaneous panniculitis-like T-cell lymphoma. Clinical presentation with dull erythematous lesions and lipoatrophy. Credit JAAD In a histologic review of 19 cases of LEP, Park et al found that most specimens revealed lymphoplasmacytic lobular panniculitis with epidermal and dermal changes of lupus, hyaline fat necrosis, and lymphoid follicles. Jun 24, 2016 Anyone with Lupus Panniculitis or Profundus? Just recently diagnosed after about a year going to see different doctors. Have nodules on both arms which looks like a bruise, but not painful. Torn if I should start plaquenil. Some people I know told me not to start it yet, but to eat healthier, eat lots of greens, go organic, take Vit. Just recently diagnosed after about a year going to see different doctors. We have only had a few members come thru with Lupus Panniculitis (Profundus), and I don't believe any of them have posted in the last few months. After an inflammatory phase of weeks to months, panniculitis often settles down. Some forms of panniculitis do not leave a mark, but destructive forms of panniculitis tend to leave a permanent dent in the skin. Hydroxychloroquine lupus panniculitis Lupus Panniculitis pictures of lupus, The challenge of identifying identical twins Advances in. Hydroxychloroquine moa lupus Lupus in lupus pernio is misleading because it suggests a connection with systemic lupus erythematosus; lupus pernio is actually a finding of the skin in sarcoidosis. lupus profundus A deeply scarring, atrophic rash occasionally found in patients with systemic lupus erythematosus, caused by inflammation of subcutaneous fatty tissue. Lupus panniculitis, lupus profundus definition of lupus.. Lupus Panniculitis/Profundus -. Panniculitis DermNet NZ. Lupus erythematosus panniculitis LEP is characterized by chronic and recurrent subcutaneous inflammatory lesions and is considered a form of chronic cutaneous lupus erythematosus CLE. Clinically, LEP appears as erythematous, deeply indurated, tender plaques and nodules. Hydroxychloroquine is mainly used to treat malaria, but has a wide variety of uses in dermatology. It may be used in the treatment of the following skin conditions Cutaneous and systemic lupus. Rheumatoid arthritis. Dermatomyositis. Polymorphic light eruption. Sarcoidosis. Granuloma annulare. Six patients are described in whom panniculitis was a major manifestation of systemic lupus erythematosus. These patients were seen in a combined-clinics population of 270 patients with systemic lupus erythematosus for an incidence of approximately 2%.