For the self-injectable solution, you can receive the injection from a healthcare provider. Or, if your healthcare provider feels you’re capable, they can train you or a caregiver to administer the drug at home. Is hydroxychloroquine hepatotic Hydroxychloroquine and the flu How much hydroxychloroquine can i take Plaquenil rash how long Initially retinal toxicity due to long-term use of chloroquine Aralen for malaria was reported in 1959 by Hobbs et al. 106 Currently, hydroxychloroquine sulphate Plaquenil is the quinoline agent of choice for the treatment of autoimmune diseases with a far lower incidence of adverse reactions. 107, 108 Hydroxychloroquine has been associated. Methotrexate Rasuvo, Otrexup is a self-injectable solution used to treat psoriasis and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. I do know that plaquenil is generally considered the least invasive drug, generally prescribed as the first line of treatment. Methotrexate is the most commonly prescribed DMARD, but it does come with the chance of side-effects. I never had any side-effects of dire consequence, but many on this forum have. Methotrexate self-injectable solution may be used as part of a combination therapy. Methotrexate self-injectable solution is available as a generic and as the brand-name drugs Rasuvo and Otrexup. Methotrexate and plaquenil interaction Methotrexate vs. Plaquenil - Autoimmune diseases - Inspire, Methotrexate Injection Side Effects, Dosage, Uses, and More Cheap aralen lupusPlaquenil and mucinexChloroquine diphosphate mechanism of actionHow does plaquenil treat rheumatoid arthritis Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Methotrexate or Plaquenil? DailyStrength. Effects of methotrexate and hydroxychloroquine combination.. Does anyone take methotrexate and hydroxychloroquine and has anyone had problems with hydroxychloroquine. Too many side effects of both methotrexate and Hydrochloroquine prompted my beautiful daughter to encourage me to go on a strict diet with no meds. I did check with my gp and rheumy re this. Methotrexate Moderate Hydroxychloroquine may reduce the renal clearance of methotrexate; the exact mechanism of this interaction is unknown. The mean AUC of methotrexate was increased 52% and the mean Cmax was reduced 17% when a single dose of methotrexate was given with a dose of hydroxychloroquine 200 mg oral. Dosage While in some cases, lower doses of NSAIDS are effective, in rheumatoid arthritis and other forms of inflammatory arthritis a higher dose is often required to decrease inflammation. A lower dosage can initially be used if inflammation is mild, if mechanical pain is the major problem.