Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Most common side effects of hydroxychloroquine Sketchypharm hydroxychloroquine Monday face, nose and lips swollen, I saw the doctor who said to stop the hydroxychloroquine totally and increase the prednisolone to 20 mg for 5 days then return to 4 mg per day, and if I had more swelling tongue, etc. then to seek immediate further help from the doctor or hospital. If you are allergic to hydroxychloroquine; any part of hydroxychloroquine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If you have had any eye changes or changes in eyesight due to hydroxychloroquine or drugs like this one. If you have psoriasis. If you have porphyria. Drug-induced photosensitivity refers to the development of cutaneous disease as a result of the combined effects of a chemical and light. Exposure to either the chemical or the light alone is not sufficient to induce the disease; however, when photoactivation of the chemical occurs, one or more cutaneous manifestations may arise. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine photosensitivity rash Hydroxychloroquine Plaquenil, Hydroxychloroquine Indications, Side Effects, Warnings. Plaquenil hot flashes However, patients treated with doxycycline and hydroxychloroquine are not exposed to sunlight because they commonly present photosensitivity, including sunburn, photosensitive eruptions, blistering, rash, pruritus, and photo-onycholysis 7, 8. Our study was based on the experience of a medical doctor who was treated for 1 year with doxycycline. Vitamin D and Prolonged Treatment with Photosensitivity.. Drug-Induced Photosensitivity Background, Pathophysiology.. Photosensitivity A Side Effect of RA Medications. The cutaneous manifestations of lupus can include malar rash, discoid rash, and photosensitivity. some may require systemic therapy with an antimalarial agent, such as hydroxychloroquine. 10. Photosensitivity reaction is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months, also take medication Humira, and have Pain Re Plaquenil and Sun Exposure Reply #13 on June 12, 2011, AM After a long dark winter of seeing no sun, I finally went into the sun for an hour, early in the morning, and over the next day, developed a red raised rash on all exposed parts, a rash that lasted for several weeks.