Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take leflunomide with all of your drugs and health problems. Does plaquenil help restore hair loss Will plaquenil help anemia Pictures of chloroquine tablets Lupus fog plaquenil Leflunomide is the generic form of the brand-name medicine Arava, which is used to treat rheumatoid arthritis a condition in which the body attacks its own joints. This prescription medication. The study is based on leflunomide and hydroxychloroquine sulfate the active ingredients of Arava and Plaquenil, respectively, and Arava and Plaquenil the brand names. Other drugs that have the same active ingredients e.g. generic drugs are not considered. A combination of leflunomide and hydroxychloroquine significantly reduced disease activity, increased salivary flow, and improved patient-perceived health in patients with primary Sjögren’s syndrome, a pilot trial showed. Findings of the trial were revealed at the recent American College of. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Leflunomide and hydroxychloroquine Leflunomide-hydroxychloroquine combo shows promise in primary Sjögren’s., Arava and Plaquenil drug interactions - eHealthMe Chloroquine dosing prophylaxisPlaquenil lupus weight loss Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. Check the latest outcomes from 29,904 Leflunomide users, or browse all drugs. Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. Leflunomide, Plaquenil, Gabapentin for a 53-year old woman.. Pilot Trial in Sjögren’s Shows Potential of Leflunomide-Hydroxychloroquine. Leflunomide Arava. Hydroxychloroquine in vitro most strongly inhibits proliferation of B-cells, production of CXCL13, IFN-α, and immunoglobulins. Their combination additively decreases lymphocyte proliferation and cytokine- and immunoglobulin production. Since leflunomide and hydroxychloroquine combination therapy Background/Purpose Primary Sjogren’s syndrome pSS is a systemic, progressive autoimmune disease characterized by secretory gland dysfunction which lacks effective therapy. Clinical trials in patients with pSS using leflunomide LEF or hydroxychloroquine HCQ previously effectively inhibited B cell hyperactivity, but induced only modest insignificant effects on clinical parameters. LEF. Caution should be used when leflunomide is given with other drugs that have the potential to cause liver injury. hydroxychloroquine, acetaminophen, non-steroidal anti-inflammatory drugs, and.