Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil kidneys Can plaquenil help skin cancer Sep 13, 2019 Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Allergic reaction from generic to plaquenil Any difference with Brand Plaquenil or Generic - HealthBoards, Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings. Does plaquenil cause coughingChloroquine treatment typing discrepancy Since the drug is cumulative in its effects you may be having an allergic reaction. My Father had the same reaction took him 3 weeks to develop it and he had to stop. It took 2 weeks for the rash to go away, but it was the Plaquenil. Now he's on Methotrexate and doing well. Plaquenil = Rash? lupus. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine Side Effects Common, Severe, Long Term -. What is Plaquenil? Plaquenil is a drug used in the acute treatment of malaria. It is also used in the long –term treatment of rheumatoid arthritis and lupus erythematosus. Its generic name is hydroxychloroquine sulfate. Chloroquine has been replaced with hydroxychloroquine as it has less side effects. Eye Exam Before Starting Treatment That's a real common side effect of Lupus is unexplained rashes. If you've ever had an allergic reaction to a drug then this is the type of reaction you'd have if you were allergic to the Plaquenil; and they'd stay until the Plaquenil was out of your system. If they're coming and going more than likely it isn't the Plaquenil. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.