While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "I was on this hydroxychloroquine for 6 months and then suddenly developed severe itching (burning like sensation, worse than any itch I have ever had) and rash that went from my neck to my feet. Plaquenil and radiation therapy toxiciy Does plaquenil reduce swelling Plaquenil hydroxychloroquine alternative medicine Jan 25, 2012 It has helped a bit with the inflammation but on reading various items on the Internet, Plaquenil seems to be for joint pain and inflammation but skin is not mentioned. I seem to be able to keep that in check with my daily Pilates and if that is its main effect I would rather not take it. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Aug 09, 2016 Plaquenil helps many, although studies are inadequate to prove this either way. The studies are too small and too short. It takes months to kick in, and up to 2 years to get full benefit. There are no large studies to look at this long term. Most Sjögrens experts agree it helps many patients. While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. Plaquenil (hydroxychloroquine) is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Plaquenil helps fatigue Does plaquenil help with fatigue. DailyStrength, Hydroxychloroquine Plaquenil Plaquenil and being in the sun Nov 16, 2018 Plaquenil is an antimalarial medication that is also commonly prescribed for a variety of chronic illnesses. I take it to help combat fatigue, and the difference it makes is pleasantly surprising. Exercise and iron infusions have done the brunt of the work. Things that Changed My Life with Lupus Fatigue, Part 3. Sjögrens Fatigue – an Autoimmune Conundrum! SjögrensLife. Is extreme fatigue a side effect of Plaquenil - NRAS. May 25, 2010 I've never heard of anyone having fatigue from plaquenil since I've been on these forums. Usually, auto immune diseases and the conditions that go with them such as anemia and vitamin deficiencies cause the fatigue. I feel your pain though. I have horrible fatigue and still struggle with it. I am taking vitamins. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell. I have been on Plaquenil for years. It has not helped me with fatigue. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time.