I don't get many side effects generally, but with prednisone I DO. It does help, but this can't be a long term affair. Plaquenil is a great drug (I have no experience with it, but many people with lupus take it). I'd ask your rheumy about it and have them explain why they made that choice for you. Prednisone is an intermediate acting corticosteroid-which means it has direct anti-inflamitory properties that take effect begining in a few hours. Is plaquenil another option instead of the prednisone? It is ment to get this undercontrol now and diminish your pain. Quinacrine chloroquine antimalarial Is hydroxychloroquine a hydrocodone Chloroquine storage in retina Oct 10, 2003 I was on steroids and plaquenil for 2 years and no one ever told me about how the would contribute to my bone loss thereby causing early onset osteoporosis. I hope you are being closely watched and monitored. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Dec 15, 2010 hello hope everyone is well just a quick question, i have been on methotrexate for 2 months increasing from 7.5 to 15 and now to 25mg.weekly now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works. It has not direct anti-inflamitory properties and instead works on the immune system-though the mechanism is not known. Plaq is a longer time medication it may take two months before their is a noticable difference. Should you take plaquenil with steroids If you can't take Plaquenil DailyStrength, Plaquenil Hydroxychloroquine - Side Effects, Dosage. Hydroxychloroquine sulfate tablets uspPlaquenil for lichen planusChloroquine resistance indiaDoes plaquenil cause coughingCan i take ibuprofen with plaquenil Medical treatment for lupus has made great strides within the last 50 years. This article will help you understand lupus treatments, lupus medications and side effects, and important lifestyle. Lupus Medications and Treatments. Methotrexate and plaquenil -. Taking Plaquenil for Rheumatoid Arthritis. Side effects of Plaquenil and prednisone that are similar include nausea, vomiting, or headache. Side effects of Plaquenil that are different from prednisone include stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, ringing in your ears, mood changes, nervousness, irritability, skin rash, itching, or hair loss. There are guidelines on the amount of Plaquenil a person should be able to take safely in a lifetime, and Katz encourages those taking the medication to discuss this with their ophthalmologists. “I think there are some people, like Ann, whose bodies, for whatever reason, don’t metabolize drugs as well,” he says. You and your doctor should decide whether you’ll take this medication or breastfeed. For seniors This drug is processed by your kidneys. Older adults with reduced kidney function may not be.