Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine 200 mg for lupus Chloroquine hydroxychloroquine Stress and anxiety is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Pain. Dr stopped Hydroxychloroquine plaquenil yesterday fearing it is now doing more harm than good. Over all I do feel it may have caused increased anxiety and depression and irritability.however lupus alone can trigger those symptoms I'm sure. She had a previous diagnosis of borderline personality disorder with symptoms of anxiety and depression without treatment at this time. After the diagnosis of SLE, treatment with prednisone 10 mg and hydroxychloroquine 200 mg every 24 hours was started, with improvement of the arthritis. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine and anxiety Hydroxychloroquine Plaquenil, PLAQUENIL Side Effects, Reviews by Patients - Plaquenil sarcoidosis uveitis View detailed reports from patients taking Hydroxychloroquine Sulfate who experienced anxiety. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. Hydroxychloroquine Sulfate Anxiety Reports - DrugInformer. Psychiatric symptoms induced by hydroxychloroquine - J A Gonzalez-Nieto.. Anxiety, depression and suicidal ideation in patients with.. But again- over several months time my anxiety, depression, and sense of distance from personal relationships began to worsen. It happens so subtly that I don’t realize it. Finally I found myself with the old morning anxiety, unable to face the day, helpless feeling about the future, feeling I would be unable to go forward with plans, etc. Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells. Plaquenil hydroxychloroquine Plaquenil hydroxychloroquine has many side effects. Some common ones include dizziness, abdominal pain, headache, nausea, diarrhea, itching, and sensitiviy to sun. More serious side effects which are more rare include certain types of anemia, muscle pain, and liver problems, among others.