Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Can plaquenil cause low white blood cell count Chloroquine ic50 3d7 Can plaquenil cause bone loss Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection. per kilogram kg of body weight one 200 mg tablet = 155 mg base. Feb 19, 2020 Do not exceed 600 mg or 6.5 mg/kg 5 mg/kg base per day, whichever is lower, as the incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Corticosteroids and salicylates may be used in conjunction with PLAQUENIL, and they can generally be decreased gradually in dosage or eliminated after a maintenance dose of PLAQUENIL has been achieved. Dec 30, 2015 SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil max dosage mg kg Hydroxychloroquine Dosage Guide with Precautions -, Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Guidelines for plaquenil screening The dosage for adults may also be calculated on the basis of body weight; this method is preferred for infants and children. A total dose representing 25 mg of base per kg of body weight is administered in three days, as follows First dose 10 mg base per kg but not exceeding a single dose of 620 mg base. Second dose 5 mg base per kg but. PLAQUENIL® - Food and Drug Administration. ACR Actual-weight hydroxychloroquine dosing works in SLE, up.. Plaquenil toxicity and lowering dosage What You Sjo. The current American Academy of Ophthalmology AAO guidelines, published in 2016, recommend a maximum daily hydroxychloroquine dose of ≤5.0 mg/kg of real weight. These guidelines were established to minimize the likelihood of permanent vision loss related to hydroxychloroquine retinopathy. Aug 30, 2011 A daily dose of 6.5mg/kg ideal body weight places patients at higher risk, but a daily dose below this level did not preclude the patient from developing toxicity after many years of treatment. Mar 10, 2020 The minimum effective dose should be employed. This dose should not exceed 6.5 mg/kg/day calculated from ideal body weight and not actual body weight and will be either 200 mg or 400 mg per day. In patients able to receive 400 mg daily Initially 400 mg daily in divided doses.