Over the last six months I began to experience extremely itchy skin - I just wanted to scratch my skin off - sometimes without realising I made my arms bleed. I then, about 5 weeks ago, began to experience my eyes becoming very itchy, on the inside, they became very red and watered continuiously. Does plaquenil caus stiff legs Can you take plaquenil with milk What will happen if i don't take plaquenil May 07, 2012 Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. I had to stop plaquenil because of an itchy rash. It didn't bother me until I raised the dose above 200mg a day then it went wild. Besides the red rash I had all over I also had itchy bumps on the palms of my hands that seemed to be deep under the skin. For me the plaquenil actually gave me a horrible rash for about 2 weeks it is actually a rare side affect but it happens don't worry it goes away it starts REALLY itchy then scales then it burns then its gone i would take HOT showers to alleviate my skins irritability then load up on an oatmeal based lotion u can find this ANYWHERE but oatmeal. I could not go to work looking as I did, so I stopped taking them. I put up with this for a few days and then thought enough was enough. Fies the itching frim plaquenil stop Discontinued Plaquenil.itching skin?, Terrible Itching on Plaquenil---PLEASE HELP. Plaquenil sore more I was dropped from 400mg to 200mg Hydroxy about 6 weeks ago at the same time as I switched to injectable MTX instead of the tablets. I asked why the drop in dose and my GP read the rheumy's email and apparently Hydroxy works cumulatively so that it may be fine but can build up in your system after a period of time and that's why I was put on the lower dose as a maintenance dose so that the. Does anyone who has RA suffer with itchy skin taking. - NRAS. Itchy rash" Lupus Community - Support Group. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Severe depression and anxiety, overall itching, pain and stiffness increased instead of decreased First, my mother and sister took plaquenil for lupus with good effect, so I am not just disliking it for no good reason. I also suffer from disabling bipolar disorder. For 25 years, I have gotten hypomanic during spring. Very happy, never depressed. May 23, 2016 The typical dose for hydroxychloroquine is 200-400mg per day and is based on a person’s body weight or if you are overweight, your ideal body weight. While hydroxychloroquine is considered a relatively safe medication, like all medications there are potential risks. These include body rashes that often will itch. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.