Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine premaquin Plaquenil cause anemia Hydroxychloroquine pregnancy A 71-year-old arthritic white woman, weighing 110 pounds, presented with a feared complaint of retinal hydroxychloroquine sulfate Plaquenil toxicity. She reported a light fog, just right of her central vision, worse in the right eye than the left. Most patients do not experience many symptoms of retinal toxicity until it has progressed too far. Late stages include loss of visual acuity, peripheral vision and night vision. Patients who have been on Plaquenil longer than 5 years, are on a daily dose greater than 5mg/kg real body weight, have kidney problems or use the drug Tamoxifen may be at a higher risk for developing toxicity. End stage hydroxychloroquine toxicity leads to widespread RPE and retinal atrophy with a loss of central vision, peripheral vision, and night vision. Recent studies have shown that patients of Asian descent develop initial damage in a more peripheral extramacular distribution near the arcades, most frequently in the inferotemporal region with. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil retinal toxicity night vision Hydroxychloroquine Plaquenil Toxicity and., Reasons To See Your Retina Specialist Plaquenil Toxicity. Plaquenil and low blood sugarPlaquenil 200 costHydroxychloroquine deafnessH-chloroquine Toxicity causes a parafoveal or extramacular loss of photoreceptors and the retinal pigment epithelium layer RPE. End stage maculopathy causes a bull’s eye pattern of RPE loss as well as possible cystoid macular edema, loss of central and peripheral vision as well as night vision. Plaquenil - Eye Doctor MD. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Long-Term Side Effects of Plaquenil for Rheumatoid.. Plaquenil can produce pigment changes in the macula of the retina. The retina is the part of the back of the eye that you see with. The macula is the central part of the retina responsible for central fine vision. With Plaquenil related toxicity, the pigment in the macula can change and alter vision by producing blurring and distortion of objects. Sep 15, 2014 Advanced hydroxy- chloroquine toxicity is seen as damage and atrophy of the retina and its supporting layer, the retinal pigment epithelium, with resultant loss of central, peripheral, and/or night vision. Therefore, screening to detect early signs of retinal toxicity is crucial to try and help patients preserve vision. The issues are reading, color and night vision. Patient 2 69 year old male presents with a history of long term plaquenil use. Diagnosed with RA at age 19 now has almost no use of his hands. Has had 10 surgeries mostly joint replacements, stopped all drugs last year after a life threatening infection now starting back on therapy.