Plaquenil erg

Discussion in 'Hydroxychloroquine 200mg' started by RED FOX, 16-Mar-2020.

  1. Zonus Moderator

    Plaquenil erg


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to. Full-field electroretinography ERG has not been demonstrated to be a reliable method for identifying early hydroxychloroquine retinopathy. Results of standard ERG may be normal in early and well-established retinopathy. 11 The scotoma needs to occupy a majority of the visual field before full-field ERG results are considered abnormal. 12

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Plaquenil erg

    Plaquenil Hydroxychloroquine - Side Effects, Dosage., Hydroxychloroquine Plaquenil Toxicity and.

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  6. The electroretinogram ERG. The global or full-field electroretinogram ERG is a mass electrical response of the retina to photic stimulation. The ERG is a test used worldwide to assess the status of the retina in eye diseases in human patients and in laboratory animals used as models of retinal disease.

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    May 02, 2018 The multifocal electroretinogram multifocal ERG, mfERG provides objective information on localized retinal function to help find early toxic retinopathy. This is Why You Need Multifocal ERG if You Have Plaquenil Patients Dr. Marmor’s research team also recommended that screening should be performed within the first year of initiating therapy, and then annually after five years of Plaquenil use. The risk for retinal toxicity begins once the patient has used Plaquenil for five to seven years and/or has taken a cumulative dose of more than 1,000g. With Plaquenil Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity Therefore, 200mg of Plaquenil daily is going to be a safe dosage for virtually all adults13

     
  7. TRWKN Well-Known Member

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine Syrup 80 mg/5 ml Essential Drugs Company. Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs CHLOROQUINE Drug BNF content published by NICE
     
  8. seosap XenForo Moderator

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Anyone been treated with Plaquenil hydroxyc. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Plaquenil - FDA prescribing information, side effects and uses
     
  9. you Well-Known Member

    Hydroxychloroquine Plaquenil Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.

    Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.
     
  10. vigur Moderator

    Hydroxychloroquine A Physiologically-Based. Hydroxychloroquine HCQ is a lysosomotropic autophagy inhibitor being used in over 50 clinical trials either alone or in combination with chemotherapy. Pharmacokinetic PK and pharmacodynamic PD studies with HCQ have shown that drug exposure in the blood does not correlate with autophagy inhibition in either peripheral blood mononuclear cells or tumor tissue. To better explain this PK/PD.

    Hydroxychloroquine toxicity - EyeWiki