Please review the following URL and make sure that it is spelled correctly. Up to 60 percent of adults report that they have had nocturnal leg cramps. What drug is similiar to plaquenil Hydroxychloroquine blood monitoring Is hydroxychloroquine sulfate a steroid Jun 25, 2013 Hi, although Plaquenil is prescribed for autoimmune diseases, such as yours, it can actually add to/increase the number of the symptoms. Muscle damage and leg pain being just 2 examples. It is great that you have responded so well to the new medication. Lupus myositis often affects the muscles of your neck, pelvis, thighs, shoulders and upper arms; difficulty in climbing stairs and getting up from a chair are early symptoms. Later symptoms may include difficulty lifting objects onto a shelf, lifting your arm to comb or brush your hair, getting out of the bath. Muscle spasms can also be caused in part by dehydration. Anxiety, stress and poor sleep can contribute to a number of bodily issues, including muscular spasms. It is important to make sure to get a decent number of uninterrupted hours of sleep and to manage anxiety with breathing exercises, yoga, or other outlets. The exact mechanism is unknown, but the cramps are probably caused by muscle fatigue and nerve dysfunction rather than electrolyte or other abnormalities. The recurrent, painful tightening usually occurs in the calf muscles and can cause severe insomnia. Plaquenil and muscle spasms Myoclonus Fact Sheet National Institute of Neurological., How Lupus Affects the Muscles, Tendons and Joints Lupus. What happens if you take hydroxychloroquine without foodPlaquenil 20 mgChloroquine kidney disorders problemsU87 chloroquine in vivo View detailed reports from patients taking plaquenil who experienced muscle spasms. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. Hydroxychloroquine Sulfate Muscle Spasms Reports.. How To Stop Muscle Spasms In The Chest Chronic Body Pain. Joint Pain and Muscle Spasms DailyStrength. Myositis refers to any condition causing inflammation in muscles. Weakness, swelling, and pain are the most common myositis symptoms. Myositis causes include infection, injury, autoimmune conditions, and drug side effects. Treatment of myositis varies according to the cause. Increased blinking or spasms of the eyelid joint or muscle pain large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, and sex organs loss of hearing lower back or side pain noisy breathing painful or difficult urination red irritated eyes red skin lesions, often with a purple center A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble breathing. This is not a complete list of possible side effects.