I don't get many side effects generally, but with prednisone I DO. It does help, but this can't be a long term affair. Plaquenil is a great drug (I have no experience with it, but many people with lupus take it). I'd ask your rheumy about it and have them explain why they made that choice for you. Prednisone is an intermediate acting corticosteroid-which means it has direct anti-inflamitory properties that take effect begining in a few hours. Is plaquenil another option instead of the prednisone? It is ment to get this undercontrol now and diminish your pain. How does plaquenil help fight lupus Is plaquenil safe during pregnancy Apo hydroxychloroquine Chloroquine blood bank When my wife was first diagnosed with PMR in May, 2016, she was put on 15mg Pred. A month later, she was told to take 400mg of plaquenil daily, with the understanding that plaquenil would replace prednisone eventually. This rheumy tried to get her down to 5mg six months later, which was a total mistake. Prednisone is an intermediate acting corticosteroid-which means it has direct anti-inflamitory properties that take effect begining in a few hours. It is ment to get this undercontrol now and diminish your pain. Plaq is a longer time medication it may take two months before their is a noticable difference. Summary Drug interactions are reported among people who take Prednisone and Plaquenil together. This study is created by eHealthMe based on reports of 13,794 people who take Prednisone and Plaquenil from Food and Drug Administration FDA, and is updated regularly. It has not direct anti-inflamitory properties and instead works on the immune system-though the mechanism is not known. Plaq is a longer time medication it may take two months before their is a noticable difference. What time should i take my prednisone and my plaquenil I'm using plaquenil hydroxychloroquine 200mg and., Prednisone/Plaquenil question - Plaquenil rheumatoid arthritis dosageNatural substitute for chloroquinePlaquenil shortage 2017Hydroxychloroquine 200 mg used forQuinoric hydroxychloroquine side effects Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. Plaquenil vs. Prednisone Prescription Treatment for.. Prednisone and Plaquenil drug interactions - eHealthMe. Prednisone MedlinePlus Drug Information. My body was crashing hard with no sleep or food and basically a total water diet. I feel the dosage was way too high for someone my size, and with never taking it before, I regret it. I will never again take this pill for anything. At this point, my body hurts so bad; as if I’ve been taking it for a long period of time. Plaquenil works well, but very slowly. You will need to give it at least a 6 months trial, and don't expect much in the way of results for a couple of months. After that, you'll probably look back and realize one day that you just don't feel as sore as you did three or four months back. I've been taking prednisone for my rheumatoid arthritis, but I've heard that it can increase my chances of developing osteoporosis. How big is the risk? Answer From April Chang-Miller, M. D. Generally, the higher the dose of prednisone you take and the longer you take it, the greater the risk of osteoporosis. However, even low doses interfere.