After only 6 weeks, and barely taking half of the supplement "prescription", because I started having reflux, etc. Not entirely sure yet, and to be fair - I've been on Plaquenil since last December. Along with flare and had to back off the vitamins numerous times - nevertheless my cholesterol profile improved tremendously (triglycerides alone came down a whopping 400 points! The doctor cites the malabsorption due to the celiac as the main reason for my osteoporosis and what he called "adult rickets", and my bad cholesterol profile, especially triglycerides comes from Vit B deficiency. When was chloroquin discovered Apple cider vinegar interaction with hydroxychloroquine Chloroquine endosome In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Dec 27, 2010 But have been on Medrol, Plaquenil, and only a short time of Cellcept. My ANA went neg. But since they weaned me from 10 mg Medrol to 8- then had the eye problems, chills, diarrhea, etc, then to 6 mg, again with chills, eye problems, etc, the ANA went to 40 then 80 which I know is very low compared to before, but why does it do this? I had a slightly positive ANA and negative Sjorgens. However, i have or have had so many of the Sjorgens symptoms, including gastroparesis. Just went to the rheumatologist and he basically dismissed me. Said even healthy people can have positive ANA and that the negative Sjorgens tests mean i don' t have it. I've been sick for 10 years. I've had less aches and pains since taking triple strength fish oil. Still get fatigued and seem to have flares involving my stomach every 1 - 2 weeks since starting all of this, so I'm investigating and trying to rule out possible causes of that (one of which might be the pharmacy's switch to a different manufacturer of my generic Plaquenil that occurred at the same time). I've been doing a lot of reading and information gathering regarding celiac disease and autoimmune disease and there are so many links! ) My Vit D improved from 17 to 26 (I barely took any Vit D) a high parathyroid level returned to a normal range, and my ANA was negative for the first time in 3 years. I've never been able to stay on a statin drug - all caused major side effects. Can plaquenil cause a negative ana CONDITION it’s not a sure sign of an autoimmune disease., Do steroids and Plaquenil change the ANA results? Lupus. Biaxin and plaquenil for lyme Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. which can cause allergic reactions. Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings.. Started on Plaquenil Although Blood Work was Negative.. Lupus or not Lupus? Mayo Clinic Connect. Why hydroxychloroquine can treat primary ITP with positive ANA antibody and can't if it is negative? and what is the evidence. but it is also due to other causes, sometimes we have seen. Can Plaquenil cause a normally positive anti-dsdna to be negative? Reason I ask is bc currently I'm in a bad flare. My c3/c4 c3-61.5, c4-5.1 are low and they re-tested them two more times within a month and they're all low. Within that time frame they had me do a 24 urine bc they were concerned of kidney involvement. I know that there are many causes for a positive ANA, but does a negative ANA mean someone doesn't have lupus? Is there cause for these doctors to change their minds, or is it that many doctors just know so little about lupus, that they doubt their original dx? It would be great if you could shed a little light on this for all of us.