Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine for autoimmune Is plaquenil safe during pregnancy Hydroxychloroquine 200 mg for lupus Chloroquine and jnk inhibitor clinical trial Hydroxychloroquine HCQ is efficacious for various diseases 1,2, but can produce “bulls-eye” retinopathy that decreases vision even after discontinuance 3,4. Retinopathy can be present in 7.5% of patients after 5 or more years of HCQ treatment, increasing to 20% after 20 years 2. Toxicity from hydroxychloroquine may be seen in two distinct areas of the eye, the cornea, and the macula. The cornea may become affected relatively commonly by an innocuous vortex keratopathy characterized by whorl-like corneal epithelial deposits. Hydroxychloroquine HCQ is an antimalarial medication that can also be used to treat autoimmune diseases. However, it can produce irreversible changes to the retina that lead to visual impairment. The aim of this study was to determine the proportion. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Eye toxicity hydroxychloroquine HCQ Retinopathy Update 2019 - Acuity Eye Center, Hydroxchloroquine and Chloroquine Toxicity - Eye Lessons Hydroxychloroquine plaquenil direct sun lightChloroquine for malaria prophylaxis dosingDoes plaquenil effect healing after surgery The number of patients taking hydroxychloroquine is increasing and monitoring patients on therapy is challenging in the currently over stretched hospital eye service. A recent paper estimates. Monitoring for hydroxychloroquine retinopathy Eye. Retinal Toxicity in Patients Treated With Hydroxychloroquine.. Bull's-eye maculopathy due to hydroxychloroquine toxicity. By 2/2010 things were so dim I could not see to shop in stores. I quit taking Plaquenil but the DR still said no toxicity. My eyes continued to get worst. In tears I went back in July he finally sent me to a retina specialist. You don't have to have Bulls eye damage to have toxicity Over weight women over 60 should beware of taking Plaquenil. In 1962, J Lawton Smith coined the term bull's eye maculopathy, regarded as the classic finding of macular toxicity. Many reports on chloroquine retinopathy exist. In contrast, only a few cases of hydroxychloroquine toxicity have been reported. We now know that bull’s-eye maculopathy is a late finding and may be associated with vision loss. Asians have a slightly different clinical presentation 3-4. Several recent studies have shown that instead of the classic perifoveal changes typical of hydroxychloroquine toxicity, Asians with retinal toxicity have a more peripheral pattern.