Alternatively, we suggest using this opportunity to take a little break from work and read some of the interesting articles below. There are various types of cutaneous LE, classified as acute, subacute, intermittent and chronic cutaneous LE. Hydroxychloroquine ingredients Plaquenil westport ct visual field Does plaquenil increase risk of infection Chloroquine dna Background. Discoid lupus erythematosus DLE is a form of skin inflammation which occurs particularly on sun-exposed skin and can cause forms of cutaneous lupus erythematosus are most common in women of childbearing age, which is important because some treatments, including thalidomide and acitretin, can cause birth defects, and hydroxychloroquine may cause damage to the eye or ear. The revised Cutaneous Lupus Erythematosus Disease Area and Severity Index RCLASI can be used to assess disease activity and damage. Acute cutaneous lupus erythematosus. Acute cutaneous LE affects at least 50% of patients with systemic lupus erythematosus SLE. Many are sick, young, fair-skinned females. A randomized, double‐blind, multicentre study was performed to compare the efficacy of acitretin 50 mg/day with hydroxychloroquine 400 mg/day in 28 and 30 patients, respectively, suffering from cutaneous lupus erythematosus LE. The study was carried out over an 8‐week period. Acute cutaneous LE affects at least 50% of patients with systemic lupus erythematosus (SLE). Specific features of acute cutaneous LE may include: See more images of systemic lupus erythematosus. The revised Cutaneous Lupus Erythematosus Disease Area and Severity Index (RCLASI) can be used to assess disease activity and damage. Treatment of cutaneous lupus erythematosus with acitretin and hydroxychloroquine Discoid Lupus Erythematosus Medication Antimalarial agents., Cutaneous lupus erythematosus DermNet NZ Plaquenil and blood clotsPlaquenil plmDo you need to stop hydroxychloroquine before surgeryChoi et al 2014 chloroquine paclitaxel Cutaneous lupus erythematosus CLE is the second most common presenting symptom of autoimmune lupus erythematosus LE. Lesions precede the onset of systemic symptoms in 25 percent of patients, many of whom present to dermatologists for their initial evaluation.1 Prompt diagnosis of CLE requires a thorough understanding of the cutaneous manifestations and clinical spectrum of lupus. Treatment of Cutaneous Lupus Erythematosus. Treatment of cutaneous lupus erythematosus with acitretin.. Cutaneous lupus erythematosus Diagnosis and treatment.. Skin changes are common when you have lupus, but you don't have to let them get the best of you. Medical treatment can get rid of some. You can also protect your skin and use cover-up tricks to. The emphasis is on symptomatic treatment and only very rarely is it necessary to resort to high-dose systemic steroids or immunosuppressive agents for skin disease per se. Treatment of the skin in lupus often needs a multidisciplinary approach. Cutaneous lupus erythematosus encompasses a wide range of dermatologic manifestations, which may or may not be associated with the development of systemic disease. Cutaneous lupus is divided into several subtypes, including acute cutaneous lupus erythematosus, subacute cutaneous lupus erythematosus, and chronic cutaneous lupus erythematosus.