It is very important that you keep your sugar under control. Very hard to control the lupus, but the sugar you have more ability to help with diet and exercise and meds. Plaquenil discontinuation syndrome Hydroxychloroquine 12.5mg Plaquenil safe to take Combining telbivudine Tyzeka and hydroxychloroquine may increase the risk of unexplained muscle pain, tenderness, or weakness because both drugs cause such side effects. Hydroxychloroquine suppresses the immune system and should not be combined with drugs that also suppress the immune system or live vaccines. Mar 07, 2011 So back to the Sjogren's World Forums participant this person noticed that after beginning to take Plaquenil, it became more difficult to keep her diabetes in control occasionally her blood sugar became too low and she had symptoms of hypoglycemia feeling very anxious, tremor, feeling suddenly very hungry, perspiring heavily, and feeling. And perform a test for blood sugar levels. Before treatment with Plaquenil, inform the doctor if • you are allergic to quinine. • you suffer from eye problems. • you suffer from low blood sugar levels hypoglycemia. Plaquenil may increase the risk of low blood sugar levels. • you suffer from one or more of the following conditions I do not know if you are taking them, but most "lupies" do at one point or another. Taking steroids will play havoc on your sugar levels. Plaquenil increases sugar levels Plaquenil Side Effects Common, Severe, Long Term -, Reasonably Well Plaquenil and Hypoglycemia Chloroquine lysosome inhibitorPlaquenil side effects diarrheaHydroxychloroquine erectile dysfunctionWhat eye exam is needed for plaquenilShould i take plaquenil Yes, plaquenil can cause low blood sugars. Eat frequent meals with carbs and protein but good carbs with fiber like oatmeal or whole wheat toast with peanut butter. I like the lowered blood sugar effect b/c I have type 2 diabetes but before I got type 2, I had some low sugars with plaquenil for sure. Plaquenil and low blood sugar -. Plaquenil - Ministry of Health. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints.