Chloroquine phosphate resistant malaria

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  1. kiber XenForo Moderator

    Chloroquine phosphate resistant malaria


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase. Patients in whom chloroquine or hydroxychloroquine have failed to prevent or cure clinical malaria or parasitemia, or patients who acquired malaria in a geographic area where chloroquine resistance. Chloroquine Phosphate. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Chloroquine phosphate resistant malaria

    Chloroquine - FDA prescribing information, side effects and uses, CHLOROQUINE PHOSPHATE, USP

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  7. Dubawa checks found not only Chloroquine Phosphate as the only purported remedial treatments for coronavirus, but reports also named Favipiravir and Remdesivir. Global Times China and China Science on their verified Twitter handle attested to the fact that Chloroquine Phosphate an anti-malaria treatment drug has proven effective in treating Covid-19.

    • Chloroquine Does NOT Cure Coronavirus! Dubawa.
    • Chloroquine Phosphate - WebMD.
    • Chloroquine Dosage Guide with Precautions -.

    OverviewMedical usesAdverse effectsOverdoseResistance in malaria Chloroquine needs to be taken 1-2 weeks before traveling to an area with malaria, compared to some alternatives that can be taken 1-2 days before. chloroquine is only effective against malaria from certain areas of the world. chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions. CDC Malaria Hotline 770 488-7788 or 855 856-4713 toll free Monday –Friday, 9 am to 5 pm EST; 770 488-7100 after hours, weekends, and holidays 1 If a person develops malaria while taking chemoprophylaxis, that particular drug should not be used as a part of their treatment regimen. Use one of the other options instead.

     
  8. Nowell Moderator

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  9. ColdFusion Well-Known Member

    Drug Safety in Pregnant & Nursing Women These drugs are pregnancy category B drugs during the first stages of pregnancy. After 30 weeks of gestation, NSAIDs and high-dose aspirin may increase the risk of a type of fetal heart problem and high-dose aspirin may increase the risk for fetal bleeding or bruising.

    Systematic review of hydroxychloroquine use in pregnant.