Even if you run a profile in Epocrates , it is impossible to tell whether a combination with another drug may lead to interaction. To understand the risks and benefits of these medications, please discuss it with your doctors. Read more Neither of your medications interact w/ Tylenol (acetaminophen) but the do have a possible interaction w/ each other. Thus you will require close monitoring by your doctor and be on the lookout for any adverse effects. It's not major, but it can make you more dizzy, drowsy, and lower your ability to think as clearly. Read more I would be most concerned about the effects on the kidney. Hydroxychloroquine vs plaquenil What does quinine and chloroquine treat Does plaquenil have blood thinning properties Aspirin and caffeine may also be used for purposes not listed in this medication guide. Aspirin may cause stomach or intestinal bleeding, which can be fatal. Aspirin can also cause a severe allergic reaction. Get emergency medical help if you have hives, wheezing, or swelling in your face, lips, tongue. It may increase your risk of side effects. Taking cyclosporine with hydroxychloroquine can increase the amount of cyclosporine in your body. This may increase your risk of side effects from cyclosporine. Disclaimer Our goal is to provide you with the most relevant and current information. If you do Would consider alternating them, and not taking the maximum allowable dose for each, rather take less 25% less than that. If you have hepatitis or bad liver would not take tylenol; or bad kidney or allergies to anti-inflammatory medicine/aspirin, would not take aleve naproxen. If you do notice this sort of thing, discuss it w/ your doctor - but you can take Tylenol (acetaminophen) as directed w/out fear. Nabumetome (relafen) can be pretty hard on the stomach, can cause platelet dysfunction, might have additive effects on the kidney which isn't usually a problem. You are too young to be placed on these medications for any long period of time. Read more See 1 more doctor answer Tylenol (acetaminophen) and Codeine can be taken safely together under physician supervision. Can you take hydroxychloroquine and aspirin Drugs & Medications - WebMD, Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil and vision side effectsPlaquenil and ibuprophen Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Plaquenil interaction acetaminophen - Answers on HealthTap. Plaquenil and Aspirin drug interactions - eHealthMe. HYDROXYCHLOROQUINE/DIGOXIN; Moderate Interactions. These medications may cause some risk when taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in formation. These effects are more likely if you are taking a higher dose of methotrexate, such as doses used in the treatment of cancer or severe psoriasis, or if you are regularly taking higher doses of aspirin, e.g. more than 4 adult-strength aspirin tablets per day. I started taking plaquenil seven years ago and i feel that it has really helped me, I feel much better. I know that it helps with the joint pain but it also is bad for other parts of your body. Lately i feel like my eye sight is getting really bad. I feel it can help you but it can also hurt you. I have stopped taking this medication one week ago.