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    Diabetes mellitus ist eine chronische Stoffwechselerkrankung, die durch einen erhöhten Blutzuckerspiegel (Hyperglykämie) gekennzeichnet ist. Ursache ist entweder ein Insulinmangel, eine Insulinunempfindlichkeit (Insulinresistenz) oder beides. Diabetes mellitus kommt hauptsächlich in zwei Formen vor: Typ-1-Diabetes entsteht durch einen Mangel am Hormon Insulin. Körpereigene Abwehrstoffe (Antikörper) zerstören die Insulin produzierenden Zellen der Bauchspeicheldrüse. Diese Form beginnt meist schon im Kindes- oder Jugendalter. Typ-2-Diabetes entsteht zum einen durch eine verminderte Empfindlichkeit der Körperzellen für Insulin (Insulinresistenz). Zum anderen führt eine jahrelange Überproduktion von Insulin zu einer "Erschöpfung" der Insulin produzierenden Zellen. cialis define The impotence drug Viagra may help ward off type 2 diabetes in people already at risk for the illness, a small new trial suggests. Insulin sensitivity involves the body's ability to efficiently use the hormone. National Institutes of Health, found that Viagra (sildenafil) improved "insulin sensitivity" in overweight, pre-diabetic people. Small trial The erectile dysfunction drug was also tied to a lowering of levels of a marker associated with a raised risk of heart and kidney disease, the researchers reported in the Read: 15 ways to prevent or manage diabetes However, the trial was small with just 42 patients and "further studies will be needed to determine whether long-term treatment with drugs like sildenafil can prevent the onset of diabetes in high-risk patients", study lead author Dr Nancy Brown said in a journal news release. Brown and her colleagues at Vanderbilt University School of Medicine in Nashville tracked outcomes for 42 overweight men and women with pre-diabetes. All of the patients were randomly assigned to take Viagra (25 milligrams, three times per day) or an inactive placebo for three months. By the end of that time, those in the Viagra group were more sensitive to insulin and also had lower levels of albumin in their urine (a marker of heart and kidney disease risk) than those in the placebo group, the researchers found. Without treatment, as many as 30 percent of people with pre-diabetes go on to develop type 2 diabetes within five years, Brown's team pointed out. "Because existing drug therapies to prevent type 2 diabetes can have negative effects on the heart or be of limited use in patients with kidney disease, strategies to prevent diabetes without adversely affecting the risk of kidney and heart disease could have a large impact on public health," she said in the news release.

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    Apr. 2015. US-amerikanische Wissenschaftler konnten zeigen, dass Sildenafil Handelsname Viagra Diabetes-bedingte Nervenschädigungen lindern. can you buy prednisone over the counter uk Erectile dysfunction is a common occurrence in men with diabetes. Since 1998, when sildenafil brand name Viagra first came on the market. Men with diabetes having trouble with achieving and/or maintaining an erection can take oral medications like sildenafil Revatio, Viagra, tadalafil Adcirca,Cialis, avanafil Stendra, or.

    It is estimated that about 35% to 75% of men with diabetes will experience at least some degree of erectile dysfunction -- also called ED or impotence -- during their lifetime. Men with diabetes tend to develop erectile dysfunction 10 to 15 years earlier than men without diabetes. As men with diabetes age, erectile dysfunction becomes even more common. Above the age of 50, the likelihood of having difficulty with an erection occurs in approximately 50% to 60% of men with diabetes. Above age 70, there is about a 95% likelihood of having some difficulty with erectile dysfunction. The causes of erectile dysfunction in men with diabetes are complex and involve impairments in nerve, blood vessel, and muscle function. To get an erection, men need healthy blood vessels, nerves, male hormones, and a desire to be sexually stimulated. US-amerikanische Wissenschaftler konnten zeigen, dass Sildenafil (Handelsname Viagra) Diabetes-bedingte Nervenschädigungen lindern könnte. Eine Schädigung der peripheren Nerven (diabetische Neuropathie) kann bei allen Formen des Diabetes auftreten und ist eine für Patienten oftmals sehr unangenehme Folgekomplikation. Die Studie ist im renommierten Fachjournal PLo S ONE erschienen. Die diabetische Neuropathie ist eine sehr häufige Folgekomplikation des Diabetes mellitus, sie kann bis zu 70 Prozent der Patienten betreffen. Infolge dauerhaft erhöhter Blutzuckerspiegel wird der Stoffwechsel der Nervenzellen gestört, schließlich kommt es zur Schädigung der Nerven. Zu den Langzeitkomplikationen gehört beispielsweise auch das diabetische Fußsyndrom. Die Wissenschaftler um Lei Wang vom Henry Ford Hospital in Detroit untersuchten im Tiermodell die Auswirkungen von Sildenafil, einem Wirkstoff der zur Behandlung der erektilen Dysfunktion eingesetzt wird, auf schon fortgeschrittene periphere Nervenschäden.

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